Metabolic Maintenance L-Metilfolato 2.5 mg - 90 Cápsulas

What is L-Methylfolate and why is it important?

L-methylfolate, also known as 5-MTHF or levomefolic acid, is the biologically active form of folate (vitamin B9). Unlike synthetic folic acid, L-methylfolate does not require enzymatic conversion to be utilized by the body, making it an ideal option for individuals with genetic variants in the MTHFR enzyme. This active form directly participates in essential processes such as methylation, neurotransmitter synthesis, and red blood cell formation. Metabolic Maintenance L-Methylfolate provides 2.5 mg (2500 µg) per capsule, a high dose that may be recommended under professional supervision in specific cases, such as supporting methylation or mood health.

Benefits of L-Methylfolate according to the EFSA

The European Food Safety Authority (EFSA) has approved health claims for folate. Although these claims apply to folate in general, L-methylfolate, being the active form, can contribute to the same effects. Scientifically supported benefits include: "folate contributes to maternal tissue growth during pregnancy" and "folate contributes to normal blood cell formation." Additionally, folate helps in the normal metabolism of homocysteine, an important factor for cardiovascular health. It is important to note that these benefits are observed in the context of a balanced diet and that supplements do not replace a varied diet.

Recommended daily dose

The recommended daily dose of folate for the general population is 400 µg per day, and during pregnancy, it is advised to increase to 600 µg, according to Spanish health authorities. However, the Metabolic Maintenance L-Methylfolate product offers 2.5 mg (2500 µg) per capsule, a much higher dose. This amount may be suitable for individuals with specific needs, such as those with MTHFR mutations that affect folate absorption, or under the recommendation of a healthcare professional. The recommended daily dose should not be exceeded without medical supervision. Consult your doctor or pharmacist before starting any supplementation.

Who is this supplement suitable for?

This supplement is especially indicated for people who wish to support their methylation process, which is fundamental for DNA synthesis, detoxification, and neurotransmitter production. It is also suitable for those with genetic variants in the MTHFR gene, which hinders the conversion of folic acid into its active form. By directly providing L-methylfolate, this metabolic step is avoided, ensuring the availability of active folate. Additionally, it can be beneficial for women of childbearing age or pregnant women who need a highly bioavailable source of folate, always under medical advice. The product is gluten-free, dairy-free, nut-free, and contains no fillers, binders, artificial flavors, or colorings.

How to choose the best folate supplement

When selecting a folate supplement, it is important to consider the form. Folic acid is the common synthetic form in many supplements, but it requires conversion through the MTHFR enzyme. L-methylfolate, like that from Metabolic Maintenance, is the active and directly usable form, making it preferable for people with absorption problems or genetic variants. The dosage is also key: while 400-800 µg is sufficient for most, higher doses may be necessary in certain therapeutic protocols. In addition, verify purity and the absence of allergens. Metabolic Maintenance, part of the Allergy Research Group, has over 45 years of experience in formulating high-quality, science-backed supplements.

Frequently asked questions

Is L-methylfolate the same as folic acid?

No. Folic acid is the synthetic form that needs to be converted into L-methylfolate in the body. This process can be inefficient in people with MTHFR variants. L-methylfolate is the active form and is ready to be used.

Can I take this product during pregnancy?

Official recommendations indicate 400-600 µg of folate per day during pregnancy. This product contains 2500 µg, a much higher dose. It should only be taken under medical supervision during pregnancy.

How long does it take to notice its effects?

The effects on blood folate levels can be observed within weeks, but the subjective perception of well-being varies among individuals. It is important to be consistent and follow professional guidance.

Food supplements should not be used as a substitute for a balanced diet. Do not exceed the recommended daily dose. Keep out of reach of young children.