Endur-Amide SR Niacinamida 500 mg - 200 Comprimidos de Liberación Sostenida

What is niacinamide and how does it work?

Niacinamide, also known as nicotinamide, is a form of vitamin B3 that differs from niacin in that it does not cause the characteristic flushing. This Endur-Amide supplement provides 500 mg per tablet in a sustained-release matrix, designed to release the active ingredient gradually over 5 to 7 hours. Niacinamide is a precursor to nicotinamide adenine dinucleotide (NAD), an essential coenzyme present in all cells of the body. NAD participates in fundamental processes such as energy metabolism, DNA repair, and cell communication, making it an ally for maintaining overall health.

By choosing a sustained-release presentation, more uniform absorption is favored and plasma peaks are avoided, which can result in better tolerance and utilization by the body. Each tablet is formulated without unnecessary ingredients, making it suitable for vegan and gluten-free diets.

Benefits supported by EFSA

The European Food Safety Authority (EFSA) has approved several health claims for niacin (vitamin B3), which are applicable to both niacin and niacinamide. These include:

• Niacin contributes to normal energy-yielding metabolism.
• Niacin contributes to the normal functioning of the nervous system.
• Niacin contributes to normal psychological function.
• Niacin contributes to the maintenance of normal skin and mucous membranes.
• Niacin contributes to the reduction of tiredness and fatigue.

These benefits are supported by extensive scientific evidence and make niacinamide a key nutrient for those seeking to maintain their energy levels, support skin health, and preserve optimal cognitive function. It is important to note that these effects are obtained within a balanced diet and a healthy lifestyle.

Sustained release: why is it important?

The sustained-release (SR) technology used in Endur-Amide uses a wax matrix that gradually releases niacinamide over 5 to 7 hours. This system offers several advantages over conventional immediate-release presentations:

• Stable plasma levels: Peaks and troughs that can occur with single doses are avoided, maintaining a more constant concentration of the nutrient in the blood.
• Less frequent dosing: A single daily dose may be sufficient to maintain benefits throughout the day.
• Improved digestive tolerance: By being released slowly, the possibility of gastrointestinal discomfort is reduced.

For people with an active lifestyle or who seek convenience, this presentation facilitates adherence to the supplement without sacrificing optimal bioavailability.

Who is this supplement suitable for?

Endur-Amide SR Niacinamide 500 mg is suitable for adults who wish to supplement their vitamin B3 intake, especially those with specific needs:

• People on restrictive diets: Vegans or vegetarians may have a lower intake of niacin through their diet, as animal sources are rich in this vitamin. This supplement is 100% plant-based.
• Those looking to support skin health: Niacinamide is known for its role in maintaining the skin barrier and improving skin appearance.
• Individuals with fatigue or low energy: By contributing to energy metabolism, it can help reduce feelings of tiredness.
• Athletes or active people: Cellular energy production is crucial for physical performance and recovery.

In addition, the product is free of common allergens such as gluten, soy, dairy, and artificial preservatives, making it suitable for people with food sensitivities.

Recommended dosage and use

It is recommended to take one tablet daily, preferably with a meal, to facilitate absorption. Do not exceed the recommended daily dose without consulting a healthcare professional beforehand. Sustained-release tablets should not be chewed or crushed, as this would alter their release mechanism. It is important to keep the container closed in a cool, dry place, protected from light and humidity.

For people who require higher doses under medical indication, professional supervision is essential, as high doses of niacinamide can affect liver function or interact with certain medications.

Possible side effects and precautions

Niacinamide is generally well tolerated and, unlike niacin, does not cause flushing or itching. However, at very high doses (above 500 mg per day), mild gastrointestinal discomfort, headache, or nausea may occur. If any adverse symptoms are experienced, it is recommended to reduce the dose or discontinue use and consult a doctor.

Pregnant or breastfeeding women, as well as people with liver disease, diabetes, or clotting disorders, should consult their doctor before starting supplementation. This product should not be used as a substitute for a varied and balanced diet.

As with any supplement, it is important to purchase it from reliable sources and verify that it meets quality standards. Endurance Products, a family business with over 45 years of experience, manufactures this product in the United States following good manufacturing practices.