NOW Foods, Metilfolato, 1.000 mcg, 90 comprimidos

What is Methylfolate and Why is it Important?

Discover Foods, Methyl Folate, — Methylfolate, also known as 5-methyltetrahydrofolate (5-MTHF), is the active and directly usable form of folic acid (vitamin B9). Unlike synthetic folic acid, which requires several enzymatic conversions in the body to become active, methylfolate is ready to be used by the body. This is especially relevant for people with genetic variations in the MTHFR enzyme, who may have difficulty converting conventional folic acid. NOW Foods offers this supplement in a dose of 1000 mcg per tablet, ideal for those seeking specific support for cardiovascular health, mental well-being, and pregnancy.

Benefits of Methylfolate according to EFSA

The European Food Safety Authority (EFSA) has approved several health claims for folate, which apply to methylfolate as an active form. These claims, always within the framework of a balanced diet and a healthy lifestyle, indicate that folate:

• Contributes to normal homocysteine metabolism. Elevated homocysteine levels are associated with an increased cardiovascular risk. Methylfolate helps maintain homocysteine within normal ranges.
• Contributes to normal blood cell formation. It is essential for the production of red and white blood cells.
• Contributes to the normal functioning of the immune system. Supports the body's defenses.
• Contributes to normal psychological function. It is involved in the synthesis of neurotransmitters such as serotonin.
• Contributes to the reduction of tiredness and fatigue. It participates in cellular energy production.
• Contributes to maternal tissue growth during pregnancy. Therefore, its intake is especially recommended before and during gestation.

All these statements are supported by EFSA and refer to folate in general. As an active form, methylfolate ensures that the body can benefit from these advantages even in cases of low conversion capacity.

Recommended Daily Dose and How to Take It

Each NOW Foods Methyl Folate tablet provides 1000 mcg of methylfolate (as L-5-methyltetrahydrofolate calcium). The recommended dose is one tablet daily, preferably with a meal. This amount exceeds the established daily reference intake (DRI) for adults (200 mcg) and the recommendation for pregnant women (an additional 400-600 mcg). However, doses up to 1000 mcg are considered safe and may be appropriate under professional supervision, especially in cases of confirmed deficiency or specific needs such as homocysteine reduction. Do not exceed the recommended daily dose. Consult your doctor or pharmacist before starting to take this supplement, especially if you are pregnant, breastfeeding, taking medication, or have any medical condition.

Who is this supplement suitable for?

NOW Foods Methylfolate is suitable for:

• People with the MTHFR genetic variant who have difficulty metabolizing synthetic folic acid. By directly taking the active form, the enzymatic bottleneck is avoided.
• Women planning a pregnancy or who are pregnant, as folate is key for the development of the fetal neural tube and maternal tissue growth. A dose of 1000 mcg may be recommended by a doctor in some cases.
• People with elevated homocysteine levels, as part of a comprehensive approach to cardiovascular health.
• Vegans and vegetarians, as dietary sources of folate may be insufficient, and this supplement ensures adequate intake.
• Older adults, whose nutrient absorption may be diminished.

Is methylfolate better than folic acid?

Methylfolate and folic acid are not exactly the same. Folic acid is the synthetic form found in most supplements and fortified foods. To become the active form (5-MTHF), it needs to go through several enzymatic reactions, mainly through the MTHFR enzyme. It is estimated that up to 40-60% of the population has a genetic variant that reduces the efficiency of this enzyme. In these cases, methylfolate is a direct and effective alternative. However, for people without this variant, both forms can be suitable, although methylfolate avoids any possible accumulation of unmetabolized folic acid. There is no conclusive evidence that methylfolate is superior in all cases, but it may be preferable in situations of poor absorption or specific needs. Always consult with a healthcare professional to determine which form is most suitable for you.

Frequently Asked Questions

How much folate should I take per day?

The recommended daily intake of folate for adults is 200 mcg, increasing to 400-600 mcg during pregnancy. However, doses of up to 1000 mcg are common in specific supplements and are considered safe. The optimal amount depends on your individual needs; consult your doctor.

Can I take methylfolate if I am taking medication?

Methylfolate can interact with certain medications, such as methotrexate, anticonvulsants, or oral contraceptives. Inform your doctor about all supplements you are taking to avoid interactions.

Is this product vegan?

Yes, NOW Foods Methyl Folate is suitable for vegans. The tablets do not contain animal-derived ingredients and are free of common allergens such as gluten, soy, and dairy.

How should I store the tablets?

Store in a cool, dry place, protected from light and out of reach of children. Refrigeration is not required.

Food supplements should not be used as a substitute for a balanced diet. Do not exceed the recommended daily dose. Keep out of reach of young children.