Endur Niacin IR (Immediate Release) Nicotinic Acid 500 mg, 100 Tablets

What is Vitamin B3 (Niacin)?

Vitamin B3, also known as niacin or nicotinic acid, is an essential nutrient that the body needs to convert food into energy. This water-soluble vitamin is involved in more than 200 enzymatic reactions, being key for the metabolism of carbohydrates, fats, and proteins. Niacin is naturally found in foods such as chicken, tuna, chickpeas, and peanuts, but sometimes the diet does not provide enough.

The ENDUR Niacin IR supplement offers 500 mg of pure nicotinic acid in an immediate-release formulation with a patented vegetable wax matrix. This technology allows for a gradual release of the active ingredient over approximately one hour, avoiding the sudden peak that occurs with conventional tablets. This way, absorption is optimized, and initial discomfort is minimized.

Benefits supported by the EFSA

The European Food Safety Authority (EFSA) has approved several health claims for niacin. These include:

• Energy metabolism: Niacin contributes to normal energy metabolism, helping to transform food into usable energy by cells.
• Nervous system: It promotes the normal functioning of the nervous system, which can result in improved nerve impulse transmission.
• Psychological function: It supports normal psychological function, including aspects such as concentration and mood.
• Skin and mucous membranes: It contributes to the maintenance of skin and mucous membranes under normal conditions.
• Tiredness and fatigue: It helps reduce tiredness and fatigue, especially in situations of higher energy demand.

These benefits are backed by scientific studies and form the basis for niacin supplementation.

Forms of niacin: niacin vs niacinamide

There are two main forms of vitamin B3: nicotinic acid (niacin) and nicotinamide (niacinamide). Although both are effective, they have important differences.

Nicotinic acid is the original form found in foods and is the only one that has shown beneficial effects on lipid profile in clinical studies. However, its consumption in high doses can cause temporary skin flushing, due to vasodilation. This effect is harmless and usually disappears with continued use.

Niacinamide, on the other hand, does not cause flushing but lacks the effects on blood lipids. ENDUR uses nicotinic acid (niacin) in its formulation, taking advantage of its specific properties. If you are looking to avoid flushing, this product is not suitable; but if you want to obtain all the benefits of nicotinic acid, it is an excellent option.

Recommended dosage

Each ENDUR Niacin IR tablet contains 500 mg of nicotinic acid, a dose that is above the recommended daily intake (16 mg for men and 14 mg for women). This high amount is used for specific purposes under professional supervision. The usual dose is one tablet per day, preferably with a meal to reduce possible stomach discomfort.

It is important not to exceed the recommended dose without consulting a doctor. Doses above 500 mg per day can increase the risk of side effects such as pronounced flushing or liver discomfort. It is always advisable to start with a lower dose and gradually increase it to allow the body to adapt.

Possible side effects

The most well-known side effect of niacin is facial flushing, characterized by a sensation of warmth and redness in the face, neck, and chest. This effect is more common with immediate-release forms and usually lasts between 15 and 30 minutes. To minimize it, it is recommended to take the tablet with food or use extended-release formulations like ENDUR, which gradually releases the active ingredient.

Other possible effects include mild digestive discomfort, itching, or skin rashes. In rare cases, very high doses can affect liver function. If you experience any worrying symptoms, stop consumption and consult a healthcare professional. As with any supplement, it is important to keep it out of the reach of children and store it in a cool, dry place.

Who should take niacin supplements?

Niacin supplements are indicated for people who need an extra supply of this vitamin due to restrictive diets, diagnosed deficiencies, or higher energy requirements. They are also used by those looking to support cardiovascular health and maintain normal cholesterol levels, always under medical supervision.

This product is suitable for vegans and vegetarians and is free from the most common allergens: lactose, gluten, soy, egg, fish, shellfish, nuts, wheat, corn, and yeast. Manufactured in an FDA-registered facility in the Pacific Northwest of the USA, it complies with strict good manufacturing practice standards.

If you have any medical condition, are pregnant or breastfeeding, consult your doctor before starting supplementation. Niacin can interact with certain medications, such as anticoagulants or hypoglycemic agents.